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A 'mouse trap' mechanism whereby a ligand-induced conformational transition repositions the amphi-pathic α-helix of the AF-2 activating domain and forms a transcriptionally active receptor is proposed. rm wild flower lyrics meaning The 2. dlinkap login 0-Å crystal structure of the ligand-binding domain (LBD) of the human retinoic acid receptor (RAR)-γ bound to all-trans retinoic acid reveals the ligand-binding interactions and